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Is it possible? Might Baxter’s poisoned heparin trickle down to pets? Why not? And how would we ever know?

In case you haven’t been made ware of the problem through your media sources, here’s a wrap-up: Tainted heparin, a  blood-thinning medication, was manufactured by drug company Baxter after using ingredients sourced from—you guessed it—China.

As far as I know, no one’s tried to send me an alert on the stuff. I’ve had to read the Wall Street Journal and listen to NPR to get a dose of this issue on my patients’ behalf.

Maybe that’s because I don’t use Baxter’s brand of heparin, the one responsible for 60-plus deaths in humans (primarily in dialysis centers where heparin is used as a catheter and tubing lubricating clot-buster).

I have to assume that by this time if no one’s issued an alert on the brand I DO use, that’s because it’s A-OK. My source swears their heparin’s no relation to the Baxter version. But can I help it if I’m edgy?

After all, no one sent me an alert after last year's pet food recall. And heparin is used off label for pets, meaning it's not strictly approved for their use (though a law oes allow their use "off-label" for animals). If the pet food companies didn't deign to inform me of their debacle, why would the human-focused heparin makers?

Moreover, I have no idea what my patients might look like had they received tainted heparin. What would their clinical signs be, anyway?

Would anyone investigate if another few fifteen year-old kitties with renal failure died after receiving blood transfusions laced with thinners?

If my saddle thrombus cases (precious few, thankfully) up and died? (Most do, anyway, unless treated very early.)

And how much would be too much for all the pets that have their catheters flushed with the heparin-saline solutions almost all veterinary hospitals use to maintain the intravenous catheters we use daily?

As predicted, last year’s pet food recall revealed only the tip of the iceberg when it comes to Chinese-ingredient tainted goods. Grains, drugs, toys…they’re all fair game in our brave new world of globalized trade with nations whose methods of quality control are far more lax than ours.

I certainly don’t wish to start an Internet rumor that claims your pets may become ill from the heparin they may receive. There’s absolutely no evidence that’s the case. But can we help it if our trust in the FDA and the drug companies is as tainted as the cheap Chinese ingredients we fear?

Comments
The heparin recall was announced a few weeks ago, but the suspected tainted ingredient news is fairly recent. I can't imagine the repercussions of such a widely used common drug. Sometimes I'm awestruck when news becomes so personally timely. My Mom (and my old now- deceased Sealy "Dottie") had their first observable stroke on the same day. My mom, and of course Dottie, did not seek treatment or receive heparin. When my Mom had her second and fatal stroke recently, again while hospitalized, she did not receive heparin because of bleeding danger. If she had, I would not be comfortable or at peace with the thought of a tainted drug contributing to her passing.

I feel extrememely saddened for the many families that may have grief and anger complicated by this recall and news.
# Posted By Barbara A. Albright/New Hampshire | 5/1/08 10:57 AM
I heard about the Heparin on NPR the other day and almost drove off the road when they explained that for ALL of the big drug companies, the far-upstream process starts for this particular medication starts with pig intestines, mostly from rural parts of China, that goes completely unregulated by ANYONE. Apparently the FDA only gets involved further down stream.

Of course, is easy to completely freak yourself out at all the other possibilities this opens up.... thank god for satellite radio and Fred on 44.
# Posted By Creature of Habit | 5/1/08 6:38 PM
Yeah, I think it was on the "McNeil-Lehrer News Hour" that I saw video of them makign the heparin ingredients, boiling the pig intestines in little chinese towns. The process looked totally UN-HYGIENIC.

It was really scary looking. I've never been particularly nationistic, but man -- I'm in a buy-American mode. Although with our lousy FDA that's no ironclad guarantee either.
# Posted By Stefani | 5/1/08 9:50 PM
A list of companies who have recalled products (besides Baxter). If you know which products are coated with Heparain, Dr. Patty, I'd ask the companies if they've verified it's real stuff. Don't know if symptoms would be the same in cats/dogs, but apparently pigs react same as humans.
http://www.fda.gov/cder/drug/infopage/heparin/defa...

BTW I noticed the FDA has redone their main page to look more bland and professional ! They are also going to hire a LOT more people....think it was over a thousand, but don't remember.
# Posted By CathyA | 5/2/08 7:57 AM
I'm a research scientist who works with rats and mice and uses a lot of heparin, not sourced from Baxter. Our animal facility received a letter warning us of tainted heparin (and the suspect lot numbers) more than a month ago.
# Posted By Sarah | 5/3/08 1:24 AM
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